Epidural clonidine used as an adjunct to nearby anesthetics has 3 distinct mechanisms of action. To start with, the stimulation of alpha-2-receptors while in the dorsal horn reduces suffering transmission. Secondly, clonidine can result in local vasoconstriction that limits vascular elimination of local epidural anesthetics. Master the implications for https://judyn592fgi9.ltfblog.com/profile