Crofelemer raises amounts of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe. Crofelemer has the opportunity to inhibit CYP3A4 at concentrations expected in the gut; unlikely to inhibit systemically because minimally absorbed. 4.8 Unwanted outcomes Typical extended usage of codeine is known to cause habit and tolerance. Signs or https://josepha319gns5.ktwiki.com/user